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Quantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPs

Finka, Andrija ; Sood, Vishal ; Quadroni, Manfredo ; Rios, Paolo ; Goloubinoff, Pierre

In: Cell Stress and Chaperones, 2015, vol. 20, no. 4, p. 605-620

Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis

Finka, Andrija ; Goloubinoff, Pierre

In: Cell Stress and Chaperones, 2013, vol. 18, no. 5, p. 591-605

Heat shock protein 90: a capacitor or a mutator?

Sawarkar, Ritwick ; Paro, Renato

In: Journal of Biosciences, 2010, vol. 35, no. 2, p. 163-165

Chaperones and proteases : Cellular fold-controlling factors of proteins in neurodegenerative diseases and aging

Hinault, Marie-Pierre ; Ben-Zvi, Anat ; Goloubinoff, Pierre

In: Journal of Molecular Neuroscience, 2006, vol. 30, no. 3, p. 249-265

Potential Microbiological Effects of Higher Dosing of Echinocandins

Steinbach, William J. ; Lamoth, Frédéric ; Juvvadi, Praveen R.

In: Clinical Infectious Diseases, 2015, vol. 61, p. S669-S677

Toxoplasma gondii Hsp90: potential roles in essential cellular processes of the parasite

ANGEL, SERGIO O. ; FIGUERAS, MARIA J. ; ALOMAR, MARIA L. ; ECHEVERRIA, PABLO C. ; DENG, BIN ; Tatu, Utpal

In: Parasitology, 2014, vol. 141, no. 9, p. 1138-1147

The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities

Wider, Diana ; Péli-Gulli, Marie-Pierre ; Briand, Pierre-André ; Tatu, Utpal ; Picard, Didier

In: Molecular and Biochemical Parasitology, 2009, vol. 164, no. 2, p. 147-152

Developing novel drugs against the unicellular parasite Plasmodium is complicated by the paucity of simple screening systems. Heat-shock proteins are an essential class of proteins for the parasite's cyclical life style between different cellular milieus and temperatures. The molecular chaperone Hsp90 assists a large variety of proteins, but its supporting functions for many proteins that are...