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Hitting the right spot : mechanism of action of OPB‐31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)

Brambilla, Lara ; Genini, Davide ; Laurini, Erik ; Merulla, Jessica ; Perez, Laurent ; Fermeglia, Maurizio ; Carbone, Giuseppina M. ; Pricl, Sabrina ; Catapano, Carlo V.

In: Molecular oncology, 2015, vol. 9, no. 6, p. 1194-1206

STAT3 is a key element in many oncogenic pathways and, like other transcription factors, is an attractive target for development of novel anticancer drugs. However, interfering with STAT3 functions has been a difficult task and very few small molecule inhibitors have made their way to the clinic. OPB‐31121, an anticancer compound currently in clinical trials, has been reported to affect...

Focused attention improves working memory: implications for flexible-resource and discrete-capacity models

Souza, Alessandra ; Rerko, Laura ; Lin, Hsuan-Yu ; Oberauer, Klaus

In: Attention, Perception, & Psychophysics, 2014, vol. 76, no. 7, p. 2080-2102

Modeling working memory: An interference model of complex span

Oberauer, Klaus ; Lewandowsky, Stephan ; Farrell, Simon ; Jarrold, Christopher ; Greaves, Martin

In: Psychonomic Bulletin & Review, 2012, vol. 19, no. 5, p. 779-819

Modeling working memory: a computational implementation of the Time-Based Resource-Sharing theory

Oberauer, Klaus ; Lewandowsky, Stephan

In: Psychonomic Bulletin & Review, 2011, vol. 18, no. 1, p. 10-45