In: Frontiers in immunology, 2017, vol. 8, p. 415
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In: Frontiers in immunology, 2016, vol. 7, p. 183
Chemokine biology is mediated by more complex interactions than simple monomolecular ligand–receptor interactions, as chemokines can form higher order quaternary structures, which can also be formed after binding to glycosaminoglycans (GAGs) on endothelial cells, and their receptors are found as dimers and/or oligomers at the cell surface. Due to the complexity of the chemokine binding and...
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In: Frontiers in immunology, 2018, vol. 9, p. 2118
Chemokine synergy-inducing molecules are emerging as regulating factors in cell migration. The alarmin HMGB1, in its reduced form, can complex with CXCL12 enhancing its activity on monocytes via the chemokine receptor CXCR4, while the form containing a disulfide bond, by binding to TLR2 or TLR4, initiates a cascade of events leading to production of cytokines and chemokines. So far, the...
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In: Development, 2011, vol. 138, no. 14, p. 2909-2914
The active migration of primordial germ cells (PGCs) from their site of specification towards their target is a valuable model for investigating directed cell migration within the complex environment of the developing embryo. In several vertebrates, PGC migration is guided by Cxcl12, a member of the chemokine superfamily. Interestingly, two distinct Cxcl12 paralogs are expressed in zebrafish...
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In: Surgical Endoscopy And Other Interventional Techniques, 2006, vol. 20, no. 10, p. 1607-1613
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In: Anatomy and Embryology, 2003, vol. 207, no. 4-5, p. 283-288
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In: Biomechanics and Modeling in Mechanobiology, 2008, vol. 7, no. 3, p. 215-225
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In: Angiogenesis, 2009, vol. 12, no. 1, p. 81-90
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In: Angiogenesis, 2013, vol. 16, no. 4, p. 795-807
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In: Biomechanics and Modeling in Mechanobiology, 2008, vol. 7, no. 3, p. 203-214
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