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Consortium of Swiss Academic Libraries

Nicotinic receptor channelopathies and epilepsy

Steinlein, Ortrud ; Bertrand, Daniel

In: Pflügers Archiv - European Journal of Physiology, 2010, vol. 460, no. 2, p. 495-503

Université de Fribourg

Functional and laminar dissociations between muscarinic and nicotinic cholinergic neuromodulation in the tree shrew primary visual cortex

Bhattacharyya, Anwesha ; Bießmann, Felix ; Veit, Julia ; Kretz, Robert ; Rainer, Gregor

In: European Journal of Neuroscience, 2012, vol. 35, no. 8, p. 1270-1280

Acetylcholine is an important neuromodulator involved in cognitive function. The impact of cholinergic neuromodulation on computations within the cortical microcircuit is not well understood. Here we investigate the effects of layer-specific cholinergic drug application in the tree shrew primary visual cortex during visual stimulation with drifting grating stimuli of varying contrast and...