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Pre-existing cardiovascular conditions as clinical predictors of myocarditis reporting with immune checkpoint inhibitors : a VigiBase study

Noseda, Roberta ; Ruinelli, Lorenzo ; van der Gaag, Linda C. ; Ceschi, Alessandro

In: Cancers, 2020, vol. 12, no. 11, p. 15

Up to 50% of myocarditis events developed in cancer patients upon treatment with immune checkpoint inhibitors (ICIs) are fatal. Therefore, identification of clinical risk factors predicting myocarditis onset during treatment with ICIs is important for the purpose of cardiac surveillance of high-risk patients. The aim of this retrospective matched case-control study was to assess whether...