Perfeziona i miei risultati

Protein pocket and ligand shape comparison and its application in virtual screening

Wirth, Matthias ; Volkamer, Andrea ; Zoete, Vincent ; Rippmann, Friedrich ; Michielin, Olivier ; Rarey, Matthias ; Sauer, Wolfgang

In: Journal of Computer-Aided Molecular Design, 2013, vol. 27, no. 6, p. 511-524

Shaping the interaction landscape of bioactive molecules

Gfeller, David ; Michielin, Olivier ; Zoete, Vincent

In: Bioinformatics, 2013, vol. 29, no. 23, p. 3073-3079

SwissSidechain: a molecular and structural database of non-natural sidechains

Gfeller, David ; Michielin, Olivier ; Zoete, Vincent

In: Nucleic Acids Research, 2013, vol. 41, no. D1, p. D327-D332

Fifteen years SIB Swiss Institute of Bioinformatics: life science databases, tools and support

Stockinger, Heinz ; Altenhoff, Adrian M. ; Arnold, Konstantin ; Bairoch, Amos ; Bastian, Frederic ; Bergmann, Sven ; Bougueleret, Lydie ; Bucher, Philipp ; Delorenzi, Mauro ; Lane, Lydie ; Mercier, Philippe Le ; Lisacek, Frédérique ; Michielin, Olivier ; Palagi, Patricia M. ; Rougemont, Jacques ; Schwede, Torsten ; Mering, Christian von ; Nimwegen, Erik van ; Walther, Daniel ; Xenarios, Ioannis ; Zavolan, Mihaela ; Zdobnov, Evgeny M. ; Zoete, Vincent ; Appel, Ron D.

In: Nucleic Acids Research, 2014, vol. 42, no. W1, p. W436-W441

Protein homology reveals new targets for bioactive small molecules

Gfeller, David ; Zoete, Vincent

In: Bioinformatics, 2015, vol. 31, no. 16, p. 2721-2727

SwissTargetPrediction: a web server for target prediction of bioactive small molecules

Gfeller, David ; Grosdidier, Aurélien ; Wirth, Matthias ; Daina, Antoine ; Michielin, Olivier ; Zoete, Vincent

In: Nucleic Acids Research, 2014, vol. 42, no. W1, p. W32-W38

SwissDock, a protein-small molecule docking web service based on EADock DSS

Grosdidier, Aurélien ; Zoete, Vincent ; Michielin, Olivier

In: Nucleic Acids Research, 2011, vol. 39, p. W270-W277

SwissBioisostere: a database of molecular replacements for ligand design

Wirth, Matthias ; Zoete, Vincent ; Michielin, Olivier ; Sauer, Wolfgang H. B.

In: Nucleic Acids Research, 2013, vol. 41, no. D1, p. D1137-D1143

The caveolin-binding motif of the pathogen-related yeast protein Pry1, a member of the CAP protein superfamily, is required for in vivo export of cholesteryl acetate

Choudhary, Vineet ; Darwiche, Rabih ; Gfeller, David ; Zoete, Vincent ; Michielin, Olivier ; Schneiter, Roger

In: Journal of Lipid Research, 2014, vol. 55, no. 5, p. 883-894

Proteins belonging to the CAP superfamily are present in all kingdoms of life and have been implicated in different physiological processes. Their molecular mode of action, however, is poorly understood. Saccharomyces cerevisiae expresses three members of this superfamily, pathogen-related yeast (Pry)1, -2, and -3. We have recently shown that Pry function is required for the secretion of...

Synthesis and in vitro evaluation of a novel radioligand for αvβ3 integrin receptor imaging: [¹⁸F]FPPA-c(RGDfK)

Monaco, Alessandra ; Zoete, Vincent ; Alghisi, Gian Carlo ; Rüegg, Curzio ; Michelin, Olivier ; Prior, John ; Scapozza, Leonardo ; Seimbille, Yann

In: Bioorganic & Medicinal Chemistry Letters, 2013, vol. 23, no. 22, p. 6068–6072

The development of RGD-based antagonist of αvβ3 integrin receptor has enhanced the interest in PET probes to image this receptor for the early detection of cancer, to monitor the disease progression and the response to therapy. In this work, a novel prosthetic group (N-(4-fluorophenyl)pent-4-ynamide or FPPA) for the 18F-labeling of an αvβ3 selective RGD-peptide was successfully prepared....