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    Université de Fribourg

    G-quadruplex based biosensor: A potential tool for SARS-CoV-2 detection

    Xi, Hui ; Juhas, Mario ; Zhang, Yang

    In: Biosensors and Bioelectronics, 2020, vol. 167, p. 112494

    G-quadruplex is a non-canonical nucleic acid structure formed by the folding of guanine rich DNA or RNA. The conformation and function of G-quadruplex are determined by a number of factors, including the number and polarity of nucleotide strands, the type of cations and the binding targets. Recent studies led to the discovery of additional advantageous attributes of G-quadruplex with the...

    Université de Fribourg

    Fine-grained breast cancer classification with bilinear convolutional neural networks (BCNNS)

    Liu, Weihuang ; Juhas, Mario ; Zhang, Yang

    In: Frontiers in Genetics, 2020, vol. 11, p. -

    Classification of histopathological images of cancer is challenging even for well- trained professionals, due to the fine-grained variability of the disease. Deep Convolutional Neural Networks (CNNs) showed great potential for classification of a number of the highly variable fine-grained objects. In this study, we introduce a Bilinear Convolutional Neural Networks (BCNNs) based deep learning...