Advanced Search

Refine my results

Document type

Institution

Specific Collection

Language

Author

Domain

Keyword

    Sorted by: Date of deposit
    2 results 1
    Université de Fribourg

    Regulation of vascular endothelial function by RhoA/Rho-kinase pathway : implications for cardiovascular diseases

    Viswambharan, Hema ; Yang, Zhihong (Dir.) ; Hayoz, Daniel (Codir.)

    Thèse de doctorat : Université de Fribourg, 2005 ; Nr. 1475.

    The vascular endothelium plays an important role in the maintenance of normal cardiovascular functions. It prevents smooth muscle contraction, inhibits smooth muscle cell proliferation and/or migration and exerts anti-thrombotic effects. One of the most important factors derived from endothelial cells is nitric oxide (NO) which is produced via activation of endothelial NO synthase (eNOS). eNOS...

    Université de Fribourg

    Regulation of tissue factor expression : implications for coronary artery disease

    Camici, Giovanni G. ; Yang, Zhihong (Dir.)

    Thèse de doctorat : Université de Fribourg, 2006 ; no. 1543.

    The innermost layer of a vessel, the endothelium, forms an interface between the circulating blood in the vascular lumen and the vessel wall. The endothelium functions as a.) a physical barrier between the blood and the vessel; b.) a vital source of enzymes activating and deactivating cardiovascular hormones; c.) a site of production of relaxing and contracting factors; and d.) a source of growth...

    2 results 1