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Potential biomarkers of Parkinson’s disease revealed by plasma metabolic profiling

Zhao, Huiyuan ; Wang, Cui ; Zhao, Nan ; Li, Wenxue ; Yang, Zhaofei ; Liu, Xinxin ; Le, Weidong ; Zhang, Xiaozhe

In: Journal of Chromatography B, 2018, vol. 1081–1082, p. 101–108

The plasma of Parkinson's disease (PD) patients may contain various altered metabolites associated with the risk or progression of the disease. Characterization of the abnormal metabolic pattern in PD plasma is therefore critical for the search for potential PD biomarkers. We collected blood plasma samples from PD patients and used an LC-MS based metabolomics approach to identify 17...