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Potassium restores vasorelaxation of resistance arterioles in non-hypertensive DOCA/salt fed mice

Wyss, C. ; Wang, Quing ; Golshayan, D. ; Nussberger, J. ; Burnier, M. ; Lehr, H.A. ; Schaefer, S.C.

In: Microvascular Research, 2012, vol. 84, no. 3, p. 340–344

Background: Potassium-enriched diets exert renal and cardiovascular protective effects, but the underlying mechanisms are largely unknown.Methods: Using the dorsal skinfold chamber model for intravital microscopy, we examined endothelium-dependent vasorelaxation of precapillary resistance arterioles in response to acetylcholine or the NO donor SNAP in awake mice. Experiments were performed in...