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A conserved role for p48 homologs in protecting dopaminergic neurons from oxidative stress

Dib, Peter Bou ; Gnägi, Bettina ; Daly, Fiona ; Sabado, Virginie ; Tas, Damla ; Glauser, Dominique A. ; Nagoshi, Peter Meister, Emi

In: PLoS Genet, 2014, vol. 10, no. 10, p. e1004718

Parkinson's disease (PD) is the most common neurodegenerative movement disorder characterized by the progressive loss of dopaminergic (DA) neurons. Both environmental and genetic factors are thought to contribute to the pathogenesis of PD. Although several genes linked to rare familial PD have been identified, endogenous risk factors for sporadic PD, which account for the majority of PD cases,...