Université de Fribourg

Polyaspartamide functionalized catechol-based hydrogels embedded with silver nanoparticles for antimicrobial properties

Tan, Milène ; Choi, Youngjin ; Kim, Jaeyun ; Kim, Ji-Heung ; Fromm, Katharina M.

In: Polymers, 2018, vol. 10, no. 11, p. 1188

In this study, polyaspartamide-based hydrogels were synthesized by boron-catechol coordination followed by incorporation of AgNPs into the materials. Free catechol moieties were exploited to produce AgNPs. TEM analyses displayed AgNPs of less than 20 nm in diameter and with minimum aggregation, attesting the role of hydrogels to act as an efficient template for the production of dispersed...

Université de Fribourg

Trithiocarbonate-functionalized PNiPAAm-based nanocomposites for antimicrobial properties

Tan, Milène ; Horvàth, Lenke ; Brunetto, Priscilla S. ; Fromm, Katharina M.

In: Polymers, 2018, vol. 10, no. 6, p. 665

In this study, four trithiocarbonate-functionalized PNiPAAms with different molecular weights were synthesized and used as a matrix to form composites with silver nanoparticles. Nanocomposites with several polymer-to-silver ratios P:Ag+ were prepared in order to evaluate the influence of silver loading. UV studies showed a thermoresponsive behavior of the nanocomposites with a...

Université de Fribourg

Synthesis of new polyether ether ketone derivatives with silver binding site and coordination compounds of their monomers with different silver salts

Girard, Jérôme ; Joset, Nathalie ; Crochet, Aurélien ; Tan, Milène ; Holzheu, Anja ; Brunetto, Priscilla S. ; Fromm, Katharina M.

In: Polymers, 2016, vol. 8, no. 6, p. 208

Polyether ether ketone (PEEK) is a well-known polymer used for implants and devices, especially spinal ones. To overcome the biomaterial related infection risks, 4-4′- difluorobenzophenone, the famous PEEK monomer, was modified in order to introduce binding sites for silver ions, which are well known for their antimicrobial activity. The complexation of these new monomers with different...