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Detecting selection from linked sites using an f-model

Galimberti, Marco ; Leuenberger, Christoph ; Wolf, Beat ; Szilágyi, Sándor Miklós ; Foll, Matthieu ; Wegmann, Daniel

In: Genetics, 2020, vol. 216, no. 4, p. 1205–1215

Allele frequencies vary across populations and loci, even in the presence of migration. While most differences may be due to genetic drift, divergent selection will further increase differentiation at some loci. Identifying those is key in studying local adaptation, but remains statistically challenging. A particularly elegant way to describe allele frequency differences among populations...