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Reproduction of contagious caprine pleuropneumonia reveals the ability of convalescent sera to reduce hydrogen peroxide production in vitro

Liljander, Anne ; Sacchini, Flavio ; Stoffel, Michael H. ; Schieck, Elise ; Stokar‑Regenscheit, Nadine ; Labroussaa, Fabien ; Heller, Martin ; Salt, Jeremy ; Frey, Joachim ; Falquet, Laurent ; Goovaerts, Danny ; Jores, Joerg

In: Veterinary Research, 2019, vol. 50, no. 1, p. 10

Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae is a severe disease widespread in Africa and Asia. Limited knowledge is available on the pathogenesis of this organism, mainly due to the lack of a robust in vivo challenge model and the means to do site-directed mutagenesis. This work describes the establishment of a novel caprine challenge...