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2 résultats 1
Università della Svizzera italiana

Higher-order connections between stereotyped subsets : implications for improved patient classification in CLL

Agathangelidis, Andreas ; Chatzidimitriou, Anastasia ; Gemenetzi, Katerina ; Giudicelli, Veronique ; Karypidou, Maria ; Plevova, Karla ; Davis, Zadie ; Yan, Xiao-Jie ; Jeromin, Sabine ; Schneider, Christof ; Bredo-Pedersen, Lone ; Tschumper, Renee C. ; Sutton, Lesley-Ann ; Baliakas, Panagiotis ; Scarfò, Lydia ; van Gastel, Ellen J. ; Armand, Marine ; Tausch, Eugen ; Biderman, Bella ; Baer, Constance ; Bagnara, Davide ; Navarro, Alba ; Langlois de Septenville, Anne ; Guido, Valentina ; Mitterbauer-Hohendanner, Gerlinde ; Dimovski, Aleksandar ; Brieghel, Christian ; Lawless, Sarah ; Meggendorfer, Manja ; Braazdilova, Kamila ; Ritgen, Matthias ; Facco, Monica ; Tresoldi, Cristina ; Visentin, Andrea ; Patriarca, Andrea ; Catherwood, Mark ; Bonello, Lisa ; Sudarikov, Andrey ; Vanura, Katrina ; Roumelioti, Maria ; Skuhrova-Francova, Hana ; Moysiadis, Theodoros ; Veronese, Silvio ; Giannopoulos, Krzysztof ; Mansouri, Larry ; Karan-Djurasevic, Teodora ; Sandaltzopoulos, Raphael ; Bödör, Csaba ; Fais, Franco ; Kater, Arnon ; Panovska, Irina ; Rossi, Davide ; Alshemmari, Salem ; Panagiotidis, Panagiotis ; Costeas, Paul ; Espinet Solà, Blanca ; Antic, Darko ; Foroni, Letizia ; Montillo, Marco ; Trentin, Livio ; Stavroyianni, Niki ; Gaidano, Gianluca ; Francia di Celle, Paola ; Niemann, Carsten ; Campo, Elias ; Anagnostopoulos, Achilles ; Pott, Christiane ; Fischer, Kirsten ; Hallek, Michael ; Oscier, David ; Stilgenbauer, Stephan ; Haferlach, Claudia ; Jelinek, Diane ; Chiorazzi, Nicholas ; Pospisilova, Sarka ; Lefranc, Marie-Paule ; Kossida, Sofia ; Langerak, Anton W. ; Belessi, Chrysoula ; Davi, Frederic ; Rosenquist, Richard ; Ghia, Paolo ; Stamatopoulos, Kostas

In: Blood, 2020, vol. 137, no. 10, p. 1365–1376

Chronic lymphocytic leukemia (CLL) is characterized by the existence of subsets of patients with (quasi)identical, stereotyped B cell receptor immunoglobulins (BcR IG). Patients in certain major stereotyped subsets often display remarkably consistent clinicobiological profiles, suggesting that the study of BcR IG stereotypy in CLL has important implications for understanding disease...

Università della Svizzera italiana

International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia

Condoluci, Adalgisa ; Terzi di Bergamo, Lodovico ; Langerbeins, Petra ; Hoechstetter, Manuela A. ; Herling, Carmen D. ; De Paoli, Lorenzo ; Delgado, Julio ; Rabe, Kari G. ; Gentile, Massimo ; Doubek, Michael ; Mauro, Francesca R. ; Chiodin, Giorgia ; Mattsson, Mattias ; Bahlo, Jasmin ; Cutrona, Giovanna ; Kotaskova, Jana ; Deambrogi, Clara ; Smedby, Karin E. ; Spina, Valeria ; Bruscaggin, Alessio ; Wu, Wei ; Moia, Riccardo ; Bianchi, Elena ; Gerber, Bernhard ; Zucca, Emanuele ; Gillessen, Silke ; Ghielmini, Michele ; Cavalli, Franco ; Stussi, Georg ; Hess, Mark A. ; Baumann, Tycho S. ; Neri, Antonino ; Ferrarini, Manlio ; Rosenquist, Richard ; Forconi, Francesco ; Foà, Robin ; Pospisilova, Sarka ; Morabito, Fortunato ; Stilgenbauer, Stephan ; Döhner, Hartmut ; Parikh, Sameer A. ; Wierda, William G. ; Montserrat, Emili ; Gaidano, Gianluca ; Hallek, Michael ; Rossi, Davide

In: Blood, 2020, vol. 135, no. 21, p. 1859–1869

Most patients with chronic lymphocytic leukemia (CLL) are diagnosed with early-stage disease and managed with active surveillance. The individual course of patients with early-stage CLL is heterogeneous, and their probability of needing treatment is hardly anticipated at diagnosis. We aimed at developing an international prognostic score to predict time to first treatment (TTFT) in patients...

2 résultats 1