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Discomfort and costs in epistaxis treatment

Nikolaou, Georgios ; Holzmann, David ; Soyka, Michael

In: European Archives of Oto-Rhino-Laryngology, 2013, vol. 270, no. 8, p. 2239-2244

An unusual case of nasal sarcoidosis

Pezier, Thomas ; Soyka, Michael ; Holzmann, David

In: European Journal of Plastic Surgery, 2013, vol. 36, no. 11, p. 719-722

Blood markers of alcohol use in epistaxis patients

Soyka, Michael ; Schrepfer, Thomas ; Holzmann, David

In: European Archives of Oto-Rhino-Laryngology, 2012, vol. 269, no. 8, p. 1917-1922

Genetic variations in bile acid homeostasis are not overrepresented in alcoholic cirrhosis compared to patients with heavy alcohol abuse and absent liver disease

Many, Natalie ; Stickel, Felix ; Schmitt, Johannes ; Stieger, Bruno ; Soyka, Michael ; Frei, Pascal ; Götze, Oliver ; Müllhaupt, Beat ; Geier, Andreas

In: Mutagenesis, 2012, vol. 27, no. 5, p. 567-572

Effects of the circadian rhythm gene period 1 (Per1) on psychosocial stress-Induced alcohol drinking

Dong, Li ; Bilbao, Ainhoa ; Laucht, Manfred ; Henriksson, Richard ; Yakovleva, Tatjana ; Ridinger, Monika ; Desrivieres, Sylvane ; Clarke, Toni-Kim ; Lourdusamy, Anbarasu ; Smolka, Michael N. ; Cichon, Sven ; Blomeyer, Dorothea ; Treutlein, Jens ; Perreau-Lenz, Stephanie ; Witt, Stephanie ; Leonardi-Essmann, Fernando ; Wodarz, Norbert ; Zill, Peter ; Soyka, Michael ; Albrecht, Urs ; Rietschel, Marcella ; Lathrop, Mark ; Bakalkin, Georgy ; Spanagel, Rainer ; Schumann, Gunter

In: American Journal of Psychiatry, 2011, vol. 168, no. 10, p. 1090-1098

Objective: Circadian and stress-response systems mediate environmental changes that affect alcohol drinking. Psychosocial stress is an environmental risk factor for alcohol abuse. Circadian rhythm gene period 1 (Per1) is targeted by stress hormones and is transcriptionally activated in corticotropin releasing factor-expressing cells. The authors hypothesized that Per1 is involved in ...

The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption

Spanagel, Rainer ; Pendyala, Gurudutt ; Abarca, Carolina ; Zghoul, Tarek ; Sanchis-Segura, Carles ; Magnone, Maria Chiara ; Lascorz, Jesús ; Depner, Martin ; Holzberg, David ; Soyka, Michael ; Schreiber, Stefan ; Matsuda, Fumihiko ; Lathrop, Mark ; Schumann, Gunter ; Albrecht, Urs

In: Nature Medicine, 2004, vol. 11, p. 35-42

Period (Per) genes are involved in regulation of the circadian clock and are thought to modulate several brain functions. We demonstrate that Per2Brdm1 mutant mice, which have a deletion in the PAS domain of the Per2 protein, show alterations in the glutamatergic system. Lowered expression of the glutamate transporter Eaat1 is observed in these animals, leading to reduced uptake of glutamate by...