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Sustained improvement of negative self-schema after a single ketamine infusion: an open-label study

Hasler, Gregor ; Suker, Samir ; Schoretsanitis, Georgios ; Mihov, Yoan

In: Frontiers in Neuroscience, 2020, vol. 14, p. -

Conventional antidepressants have several important limitations, including a lack of direct effects on negative self-schema, which is at the core of Beck’s cognitive theory of depression. Based on previous studies showing a positive effect of ketamine on negative cognition, we compared reductions in negative self-schema between responders and non-responders to a single infusion of ketamine....