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A multiscale study of the role of dynamin in the regulation of glucose uptake

Trouillon, Raphaël ; Letizia, M. Cristina ; Menzies, Keir J. ; Mouchiroud, Laurent ; Auwerx, Johan ; Schoonjans, Kristina ; Gijs, Martin A. M.

In: Integrative Biology, 2017, vol. 9, no. 10, p. 810-819

Hepatic glucose sensing and integrative pathways in the liver

Oosterveer, Maaike ; Schoonjans, Kristina

In: Cellular and Molecular Life Sciences, 2014, vol. 71, no. 8, p. 1453-1467

The Sirt1 activator SRT3025 provides atheroprotection in Apoe−/− mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression

Miranda, Melroy X. ; van Tits, Lambertus J. ; Lohmann, Christine ; Arsiwala, Tasneem ; Winnik, Stephan ; Tailleux, Anne ; Stein, Sokrates ; Gomes, Ana P. ; Suri, Vipin ; Ellis, James L. ; Lutz, Thomas A. ; Hottiger, Michael O. ; Sinclair, David A. ; Auwerx, Johan ; Schoonjans, Kristina ; Staels, Bart ; Lüscher, Thomas F. ; Matter, Christian M.

In: European Heart Journal, 2015, vol. 36, no. 1, p. 51-59

Β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue

Somm, Emmanuel ; Henry, Hugues ; Bruce, Stephen J. ; Aeby, Sébastien ; Rosikiewicz, Marta ; Sykiotis, Gerasimos P. ; Asrih, Mohammed ; Jornayvaz, François R. ; Denechaud, Pierre Damien ; Albrecht, Urs ; Mohammadi, Moosa ; Dwyer, Andrew ; Jr., James S. Acierno ; Schoonjans, Kristina ; Fajas, Lluis ; Greub, Gilbert ; Pitteloud, Nelly

In: JCI Insight, 2017, vol. 2, no. 8, p. -

β-Klotho (encoded by Klb) is the obligate coreceptor mediating FGF21 and FGF15/19 signaling. Klb–/– mice are refractory to beneficial action of pharmacological FGF21 treatment including stimulation of glucose utilization and thermogenesis. Here, we investigated the energy homeostasis in Klb–/– mice on high-fat diet in order to better understand the consequences of abrogating both...