In: Journal of Molecular Evolution, 2004, vol. 59, no. 1, p. 90-96
|
In: Nucleic Acids Research, 1998, vol. 26, no. 23, p. 5251-5255
|
In: Nucleic Acids Research, 2012, vol. 40, no. 3, p. 1299-1306
|
In: Nucleic Acids Research, 1996, vol. 24, no. 7, p. 1225-1228
|
In: Nucleic Acids Research, 2010, vol. 38, no. 17, p. 5833-5843
|
In: Vallesia : bulletin annuel de la Bibliothèque et des Archives cantonales du Valais, des Musées de Valère et de la Majorie = Jahrbuch der Walliser Kantonsbibliothek, des Staatsarchivs und der Museen von Valeria und Majoria, 1972, p. 241-247
|
In: Trends in Cell Biology, 2008, vol. 18, no. 1, p. 12-18
Trypanosoma brucei is a unicellular eukaryote that causes the deadly human African trypanosomiasis (‘sleeping sickness’) in humans. The parasite has a complicated lifestyle, it developmentally changes aspects of its mitochondrial function as it alternates from forms in the tsetse fly to forms adapted for life in the human bloodstream. The single mitochondrion found in each trypanosome has to...
|
In: Molecular Biology and Evolution, 2007, vol. 24, no. 5, p. 1149-1160
The mitochondrial inner and outer membranes are composed of a variety of integral membrane proteins, assembled into the membranes posttranslationally. The small translocase of the inner mitochondrial membranes (TIMs) are a group of ∼10 kDa proteins that function as chaperones to ferry the imported proteins across the mitochondrial intermembrane space to the outer and inner membranes. In yeast,...
|
In: Molecular and Cellular Biology, 2007, vol. 27, no. 19, p. 6876-6888
The pentatricopeptide repeat (PPR), a degenerate 35-amino-acid motif, defines a novel eukaryotic protein family. Plants have 400 to 500 distinct PPR proteins, whereas other eukaryotes generally have fewer than 5. The few PPR proteins that have been studied have roles in organellar gene expression, probably via direct interaction with RNA. Here we show that the parasitic protozoan Trypanosoma...
|
In: PLoS ONE, 2007, vol. 2, no. 5, p. e488
Bax-induced permeabilization of the mitochondrial outer membrane and release of cytochrome c are key events in apoptosis. Although Bax can compromise mitochondria in primitive unicellular organisms that lack a classical apoptotic machinery, it is still unclear if Bax alone is sufficient for this, or whether additional mitochondrial components are required. The protozoan parasite Giardia lamblia...
|