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Genome-wide patterns of latitudinal differentiation among populations of Drosophila melanogaster from North America

Fabian, Daniel K. ; Kapun, Martin ; Nolte, Viola ; Kofler, Robert ; Schmidt, Paul S. ; Schlötterer, Christian ; Flatt, Thomas

In: Molecular Ecology, 2012, vol. 21, no. 19, p. 4748–4769

Understanding the genetic underpinnings of adaptive change is a fundamental but largely unresolved problem in evolutionary biology. Drosophila melanogaster, an ancestrally tropical insect that has spread to temperate regions and become cosmopolitan, offers a powerful opportunity for identifying the molecular polymorphisms underlying clinal adaptation. Here, we use genome‐wide next‐...