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    Université de Fribourg

    TGFBI modulates tumour hypoxia and promotes breast cancer metastasis

    Fico, Flavia ; Santamaria‐Martínez, Albert

    In: Molecular Oncology, 2020, vol. 14, no. 12, p. 3198–3210

    Breast cancer metastasis is a complex process that depends not only on intrinsic characteristics of metastatic stem cells, but also on the particular microenvironment that supports their growth and modulates the plasticity of the system. In search for microenvironmental factors supporting cancer stem cell (CSC) growth and tumour progression to metastasis, we here investigated the role of the...