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    Università della Svizzera italiana

    Crossover or non-crossover outcomes : tailored processing of homologous recombination intermediates

    Sanchez, Aurore ; Reginato, Giordano ; Cejka, Petr

    In: Current opinion in genetics & development, 2021, vol. 71, p. 39-47

    DNA breaks may arise accidentally in vegetative cells or in a programmed manner in meiosis. The usage of a DNA template makes homologous recombination potentially error-free, however, recombination is not always accurate. Cells possess a remarkable capacity to tailor processing of recombination intermediates to fulfill a particular need. Vegetatively growing cells aim to maintain genome...