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A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 in auxin transport

Zhang, Yuqin ; Nasser, Victoria ; Pisanty, Odelia ; Omary, Moutasem ; Wulff, Nikolai ; Donato, Martin Di ; Tal, Iris ; Hauser, Felix ; Hao, Pengchao ; Roth, Ohad ; Fromm, Hillel ; Schroeder, Julian I. ; Geisler, Markus ; Nour-Eldin, Hussam Hassan ; Shani, Eilon

In: Nature Communications, 2018, vol. 9, no. 1, p. 4204

Transport of signaling molecules is of major importance for regulating plant growth, development, and responses to the environment. A prime example is the spatial- distribution of auxin, which is regulated via transporters to govern developmental patterning. A critical limitation in our ability to identify transporters by forward genetic screens is their potential functional redundancy. Here,...