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Negative association between left prefrontal GABA concentration and BDNF serum concentration in young adults

Müller, Sabrina Theresia ; Buchmann, Andreas ; Haynes, Melanie ; Ghisleni, Carmen ; Ritter, Christopher ; Tuura, Ruth ; Hasler, Gregor

In: Heliyon, 2020, vol. 6, no. 5, p. e04025

The brain's major inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and the brain-derived neurotrophic factor (BDNF) play important roles in several stress- related disorders. Magnetic resonance spectroscopy (MRS) allows for non-invasive quantification of GABA concentration in the brain. We investigated the relationship between GABA concentration in the left dorsolateral prefrontal...