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Contribution of sleep disturbances to fatigue in multiple sclerosis : a prospective study using clinical and polysomnographic parameters

Riccitelli, Gianna C. ; Disanto, Giulio ; Sacco, Rosaria ; Sparasci, Davide ; Sacco, Leonardo ; Castelnovo, Anna ; Miano, Silvia ; Manconi, Mauro ; Gobbi, Claudio ; Zecca, Chiara

In: European journal of neurology, 2021, vol. 28, no. 9, p. 9

Background and purpose: Fatigue is amongst the most frequent and disabling symptoms of multiple sclerosis and a close relation between fatigue and sleep quality has been hypothesized. In this study the contribution of sleep disturbances measured by clinical and polysomnographic parameters to fatigue in multiple sclerosis was investigated. Methods: This was a prospective instrumental study...