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Quantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPs

Finka, Andrija ; Sood, Vishal ; Quadroni, Manfredo ; Rios, Paolo ; Goloubinoff, Pierre

In: Cell Stress and Chaperones, 2015, vol. 20, no. 4, p. 605-620

Chemical crosslinking and mass spectrometry to elucidate the topology of integral membrane proteins

Debelyy, Mykhaylo O. ; Waridel, Patrice ; Quadroni, Manfredo ; Schneiter, Roger ; Conzelmann, Andreas

In: PLOS ONE, 2017, vol. 12, no. 10, p. e0186840

Here we made an attempt to obtain partial structural information on the topology of multispan integral membrane proteins of yeast by isolating organellar membranes, removing peripheral membrane proteins at pH 11.5 and introducing chemical crosslinks between vicinal amino acids either using homo- or hetero-bifunctional crosslinkers. Proteins were digested with specific proteases and the...

Closely related dermatophyte species produce different patterns of secreted proteins

Giddey, Karin ; Favre, Bertrand ; Quadroni, Manfredo ; Monod, Michel

In: FEMS Microbiology Letters, 2007, vol. 267, no. 1, p. 95-101