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Combined Treatment Strategies for Microtubule Stabilizing Agent-Resistant Tumors

Broggini-Tenzer, Angela ; Sharma, Ashish ; Nytko, Katarzyna J. ; Bender, Sabine ; Vuong, Van ; Orlowski, Katrin ; Hug, Daniel ; O'Reilly, Terence ; Pruschy, Martin

In: Journal Of The National Cancer Institute, 2015, vol. 107, no. 4, p. -

Tumor recovery by angiogenic switch from sprouting to intussusceptive angiogenesis after treatment with PTK787/ZK222584 or ionizing radiation

Hlushchuk, Ruslan ; Riesterer, Oliver ; Baum, Oliver ; Wood, Jeanette ; Gruber, Guenther ; Pruschy, Martin ; Djonov, Valentin

In: American Journal of Pathology, 2009, vol. 173, p. 1173-1185

Inhibitors of angiogenesis and radiation induce compensatory changes in the tumor vasculature both during and after treatment cessation. To assess the responses to irradiation and vascular endothelial growth factor-receptor tyrosine kinase inhibition (by the vascular endothelial growth factor tyrosine kinase inhibitor PTK787/ZK222854), mammary carcinoma allografts were investigated by vascular...