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    Université de Fribourg

    Compartment and cell-type specific hypoxia responses in the developing Drosophila brain

    Baccino-Calace, Martin ; Prieto, Daniel ; Cantera, Rafael ; Egger, Boris

    In: Biology Open, 2020, vol. 9, no. 8, p. -

    Environmental factors such as the availability of oxygen are instructive cues that regulate stem cell maintenance and differentiation. We used a genetically encoded biosensor to monitor the hypoxic state of neural cells in the larval brain of Drosophila. The biosensor reveals brain compartment and cell-type specific levels of hypoxia. The values correlate with differential tracheolation that...