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Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? : Position Paper from the Working Group on Coronary Pathophysiology and Microcirculation of the European Society of Cardiology

Vaccarino, Viola ; Badimon, Lina ; Corti, Roberto ; de Wit, Cor ; Dorobantu, Maria ; Hall, Alistair ; Koller, Akos ; Marzilli, Mario ; Pries, Axel ; Bugiardini, Raffaele

In: Cardiovascular Research, 2011, vol. 90, no. 1, p. 9-17

Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis

Buschmann, Ivo ; Pries, Axel ; Styp-Rekowska, Beata ; Hillmeister, Philipp ; Loufrani, Laurent ; Henrion, Daniel ; Shi, Yu ; Duelsner, Andre ; Hoefer, Imo ; Gatzke, Nora ; Wang, Haitao ; Lehmann, Kerstin ; Ulm, Lena ; Ritter, Zully ; Hauff, Peter ; Hlushchuk, Ruslan ; Djonov, Valentin ; Veen, Toon van ; Le Noble, Ferdinand

In: Development, 2010, vol. 137, p. 2187-2196

In the developing chicken embryo yolk sac vasculature, the expression of arterial identity genes requires arterial hemodynamic conditions. We hypothesize that arterial flow must provide a unique signal that is relevant for supporting arterial identity gene expression and is absent in veins. We analyzed factors related to flow, pressure and oxygenation in the chicken embryo vitelline...