Université de Fribourg

Establishing on-site reference values for 123I-FP-CIT SPECT (DaTSCAN®) using a cohort of individuals with non-degenerative conditions

Nicastro, Nicolas ; Garibotto, Valentina ; Poncet, Antoine ; Badoud, Simon ; Burkhard, Pierre R.

In: Molecular Imaging and Biology, 2016, vol. 18, no. 2, p. 302–312

To overcome the issue of reference values for DaTSCAN® requiring healthy controls, we propose an original approach using scans from individuals with non- degenerative conditions performed at one single center following the same acquisition protocol. Procedures: From a cohort of 970 consecutive patients, we identified 182 patients with a clinical diagnosis of non-degenerative parkinsonism or...