In: Journal of Medical Microbiology, 2017, vol. 66, no. 6, p. 842–843
Plasmid-mediated and chromosomally-encoded colistin resistance is increasingly being reported worldwide. We aimed to determine the prevalence of faecal carriage of colistin-resistant Gram-negative rod isolates in a university hospital in western France. From February to May 2016, rectal swabs from 653 patients hospitalized in various clinical settings were recovered and subsequently screened...
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In: Journal of Antimicrobial Chemotherapy, 2015, vol. 70, no. 1, p. 75-80
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In: Journal of Antimicrobial Chemotherapy, 2015, vol. 70, no. 1, p. 75-80
Objectives Alterations in the PhoPQ two-component regulatory system may be associated with colistin resistance in Klebsiella pneumoniae. MgrB is a small transmembrane protein produced upon activation of the PhoPQ signalling system, and acts as a negative regulator on this system. We investigated the role of the MgrB protein as a source of colistin resistance in a series of K. pneumoniae.Methods...
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