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Quantitative chemical biosensing by bacterial chemotaxis in microfluidic chips: Chemotaxis-microfluidic biosensor

Roggo, Clémence ; Picioreanu, Cristian ; Richard, Xavier ; Mazza, Christian ; Lintel, Harald van ; Meer, Jan Roelof van der

In: Environmental Microbiology, 2018, vol. 20, no. 1, p. 241–258

Whole-cell bacterial bioreporters are proposed as alternatives to chemical analysis of, for example, pollutants in environmental compartments. Commonly based on reporter gene induction, bioreporters produce a detectable signal within 30 min to a few hours after exposure to the chemical target, which is impractical for applications aiming at a fast response. In an attempt to attain faster...