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Structural characterization of suppressor lipids by high-resolution mass spectrometry

Rovillos, Mary Joy ; Pauling, Josch Konstantin ; Hannibal-Bach, Hans Kristian ; Vionnet, Christine ; Conzelmann, Andreas ; Ejsing, Christer S.

In: Rapid Communications in Mass Spectrometry, 2016, vol. 30, no. 20, p. 2215–2227

Rationale: Suppressor lipids were originally identified in 1993 and reported to encompass six lipid classes that enable Saccharomyces cerevisiae to live without sphingolipids. Structural characterization, using non-mass spectrometric approaches, revealed that these suppressor lipids are very long chain fatty acid (VLCFA)- containing glycerophospholipids with polar head groups that are...