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Exon–Intron differential analysis reveals the role of competing endogenous RNAs in post-transcriptional regulation of translation

Munz, Nicolas ; Cascione, Luciano ; Parmigiani, Luca ; Tarantelli, Chiara ; Rinaldi, Andrea ; Cmiljanovic, Natasa ; Cmiljanovic, Vladimir ; Giugno, Rosalba ; Bertoni, Francesco ; Napoli, Sara

In: Non-coding RNA, 2021, vol. 7, no. 2, p. 13

Stressful conditions induce the cell to save energy and activate a rescue program modulated by mammalian target of rapamycin (mTOR). Along with transcriptional and translational regulation, the cell relies also on post-transcriptional modulation to quickly adapt the translation of essential proteins. MicroRNAs play an important role in the regulation of protein translation, and their...