Résultats de la recherche

Large-scale comparison of toxin and antitoxins in Listeria monocytogenes

Agüero, José Antonio ; Akarsu, Hatice ; Aguilar-Bultet, Lisandra ; Oevermann, Anna ; Falquet, Laurent

In: Toxins, 2020, vol. 12, no. 1, p. 29

Toxin–antitoxin systems (TASs) are widely distributed in prokaryotes and encode pairs of genes involved in many bacterial biological processes and mechanisms, including pathogenesis. The TASs have not been extensively studied in Listeria monocytogenes (Lm), a pathogenic bacterium of the Firmicutes phylum causing infections in animals and humans. Using our recently published TASmania...

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Genetic separation of Listeria monocytogenes causing central nervous system infections in animals

Aguilar-Bultet, Lisandra ; Nicholson, Pamela ; Rychener, Lorenz ; Dreyer, Margaux ; Goezel, Bulent ; Origgi, Francesco C. ; Oevermann, Anna ; Frey, Joachim ; Falquet, Laurent

In: Frontiers in Cellular and Infection Microbiology, 2018, vol. 8, p. -

Listeria monocytogenes is a foodborne pathogen that causes abortion, septicemia, gastroenteritis and central nervous system (CNS) infections in ruminants and humans. L. monocytogenes strains mainly belong to two distinct phylogenetic groups, named lineages I and II. In general, clinical cases in humans and animals, in particular CNS infections, are caused by lineage I strains, while most of...