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A novel gene expression signature in peripheral blood mononuclear cells for early detection of colorectal cancer

Nichita, C. ; Ciarloni, L. ; Monnier-Benoit, S. ; Hosseinian, S. ; Dorta, G. ; Rüegg, Curzio

In: Alimentary Pharmacology & Therapeutics, 2014, vol. 39, no. 5, p. 507–517

Background: Early detection and treatment of colorectal adenomatous polyps (AP) and colorectal cancer (CRC) is associated with decreased mortality for CRC. However, accurate, non-invasive and compliant tests to screen for AP and early stages of CRC are not yet available. A blood-based screening test is highly attractive due to limited invasiveness and high acceptance rate among patients.Aim: To...