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Comparison of a novel biodegradable polymer sirolimus-eluting stent with a durable polymer everolimus-eluting stent: 5-year outcomes of the randomized bioflow-ii trial

Lefèvre, Thierry ; Haude, Michael ; Neumann, Franz-Josef ; Stang, Karl ; Skurk, Carsten ; Slagboom, Ton ; Sabaté, Manel ; Goicolea, Javier ; Barragan, Paul ; Cook, Stéphane ; Macia, Jean-Christophe ; Windecker, Stephan

In: JACC: Cardiovascular Interventions, 2018, vol. 11, no. 10, p. 995–1002

ObjectivesThe authors aimed to compare long-term data of an ultrathin cobalt- chromium stent with passive silicon carbide coating and an active biodegradable polymer that releases sirolimus (O-SES) (Orsiro, BIOTRONIK, Bülach, Switzerland) with the durable polymer-based Xience Prime everolimus-eluting stent (X-EES) (Abbott Vascular, Santa Clara, California).BackgroundBiodegradable polymer...

Statin effect on thrombin inhibitor effectiveness during percutaneous coronary intervention: a post-hoc analysis from the ISAR-REACT 3 trial

Khattab, Ahmed ; Ndrepepa, Gjin ; Schulz, Stefanie ; Neumann, Franz-Josef ; Mehilli, Julinda ; Büttner, Heinz ; Pache, Jürgen ; Seyfarth, Melchior ; Dirschinger, Josef ; Kastrati, Adnan ; Berger, Peter ; Schömig, Albert ; Richardt, Gert

In: Clinical Research in Cardiology, 2011, vol. 100, no. 7, p. 579-585

Comparison of a novel biodegradable polymer sirolimus-eluting stent With a durable polymer everolimus-eluting stent results of the randomized BIOFLOW-II trial

Windecker, Stephan ; Haude, Michael ; Neumann, Franz-Josef ; Stangl, karl ; Witzenbichler, Bernhard ; Slagboom, Ton ; Sabaté, Manel ; Goicolea, Javier ; Barragan, Paul ; Cook, Stéphane ; Piot, Christophe ; Richardt, Gert ; Merkely, Béla ; Schneider, Henrik ; Bilger, Johannes ; Erne, Paul ; Waksman, Ron ; Zaugg, Serge ; Jüni, Peter ; Lefèvre, Thierry

In: Circulation: Cardiovascular Interventions, 2015, vol. 8, no. 2, p. e001441

Background—Biodegradable polymers for release of antiproliferative drugs from drug-eluting stents aim to improve vascular healing. We assessed noninferiority of a novel ultrathin strut drug-eluting stent releasing sirolimus from a biodegradable polymer (Orsiro, O-SES) compared with the durable polymer Xience Prime everolimus-eluting stent (X-EES) in terms of the primary end...