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The effect of maternal immunisation during pregnancy on infant vaccine responses

Zimmermann, Petra ; Perrett, Kirsten P. ; Messina, Nicole L. ; Donatha, Susan ; Ritz, Nicole ; Klis, Fiona R. M. van der ; Curtis, Nigel

In: EClinicalMedicine, 2019, vol. 13, p. 21–30

Immunisation during pregnancy to protect infants against tetanus, pertussis and influenza is recommended in many countries. However, maternal antibodies can interfere with infant vaccine responses. We investigated the effect of antenatal diphtheria-tetanus-acellular pertussis (dTpa) and trivalent inactivated influenza (TIV) immunisation on specific and heterologous antibody responses to...