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Dynamic spherical harmonics approach for shape classification of migrating cells

Medyukhina, Anna ; Blickensdorf, Marco ; Cseresnyés, Zoltán ; Ruef, Nora ; Stein, Jens V. ; Figge, Marc Thilo

In: Scientific Reports, 2020, vol. 10, no. 1, p. 6072

Cell migration involves dynamic changes in cell shape. Intricate patterns of cell shape can be analyzed and classified using advanced shape descriptors, including spherical harmonics (SPHARM). Though SPHARM have been used to analyze and classify migrating cells, such classification did not exploit SPHARM spectra in their dynamics. Here, we examine whether additional information from dynamic...