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TAT-RasGAP317-326-mediated tumor cell death sensitization can occur independently of Bax and Bak

Annibaldi, Alessandro ; Heulot, Mathieu ; Martinou, Jean-Claude ; Widmann, Christian

In: Apoptosis, 2014, vol. 19, no. 4, p. 719-733

TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis

Somasekharan, Syam ; Koc, Michal ; Morizot, Alexandre ; Micheau, Olivier ; Sorensen, Poul ; Gaide, Olivier ; Andera, Ladislav ; Martinou, Jean-Claude

In: Apoptosis, 2013, vol. 18, no. 3, p. 324-336

A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression

Wilson, William C. ; Hornig-Do, Hue-Tran ; Bruni, Francesco ; Chang, Jeong Ho ; Jourdain, Alexis A. ; Martinou, Jean-Claude ; Falkenberg, Maria ; Spåhr, Henrik ; Larsson, Nils-Göran ; Lewis, Richard J. ; Hewitt, Lorraine ; Baslé, Arnaud ; Cross, Harold E. ; Tong, Liang ; Lebel, Robert R. ; Crosby, Andrew H. ; Chrzanowska-Lightowlers, Zofia M. A. ; Lightowlers, Robert N.

In: Human Molecular Genetics, 2014, vol. 23, no. 23, p. 6345-6355

Expression of mitofusin 2R94Q in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A

Cartoni, Romain ; Arnaud, Estelle ; Médard, Jean-Jacques ; Poirot, Olivier ; Courvoisier, Delphine S. ; Chrast, Roman ; Martinou, Jean-Claude

In: Brain, 2010, vol. 133, no. 5, p. 1460-1469

Temporal dissection of Bax-induced events leading to fission of the single mitochondrion in Trypanosoma brucei

Crausaz Esseiva, Anne ; Chanez, Anne-Laure ; Bochud-Allemann, Natacha ; Martinou, Jean-Claude ; Hemphill, Andrew ; Schneider, André

In: EMBO reports, 2004, vol. 5, p. 268-273

The protozoan Trypanosoma brucei has a single mitochondrion and lacks an apoptotic machinery. Here we show that expression of the proapoptotic protein Bax in T. brucei causes the release of cytochrome c, the depolarization of the mitochondrial membrane potential and mitochondrial fission. However, in contrast to mammalian cells, the three events are temporally well separated. The release of...