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Head-to-head comparison of FNA cytology vs. calcitonin measurement in FNA washout fluids (FNA-CT) to diagnose medullary thyroid carcinoma : A systematic review and meta-analysis

Trimboli, Pierpaolo ; Giannelli, Jacopo ; Marques, Bernardo ; Piccardo, Arnoldo ; Crescenzi, Anna ; Deandrea, Maurilio

In: Endocrine, 2022, no. 75, p. 33–39

Purpose: The sensitivity of cytology after fine needle aspiration (FNA-cytology) in detecting medullary thyroid carcinoma (MTC) is low. To overcome this problem, measuring calcitonin (CT) in washout fluid of FNA (FNA-CT) has been largely diffused and showed good performance. However, no evidence-based study exists comparing systematically the sensitivity of FNA-cytology and FNA-CT. This study...