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Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

Kuhn, Alexandre ; Goldstein, Darlene R. ; Hodges, Angela ; Strand, Andrew D. ; Sengstag, Thierry ; Kooperberg, Charles ; Becanovic, Kristina ; Pouladi, Mahmoud A. ; Sathasivam, Kirupa ; Cha, Jang-Ho J. ; Hannan, Anthony J. ; Hayden, Michael R. ; Leavitt, Blair R. ; Dunnett, Stephen B. ; Ferrante, Robert J. ; Albin, Roger ; Shelbourne, Peggy ; Delorenzi, Mauro ; Augood, Sarah J. ; Faull, Richard L.M. ; Olson, James M. ; Bates, Gillian P. ; Jones, Lesley ; Luthi-Carter, Ruth

In: Human Molecular Genetics, 2007, vol. 16, no. 15, p. 1845-1861

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Regional and cellular gene expression changes in human Huntington's disease brain

Hodges, Angela ; Strand, Andrew D. ; Aragaki, Aaron K. ; Kuhn, Alexandre ; Sengstag, Thierry ; Hughes, Gareth ; Elliston, Lyn A. ; Hartog, Cathy ; Goldstein, Darlene R. ; Thu, Doris ; Hollingsworth, Zane R. ; Collin, Francois ; Synek, Beth ; Holmans, Peter A. ; Young, Anne B. ; Wexler, Nancy S. ; Delorenzi, Mauro ; Kooperberg, Charles ; Augood, Sarah J. ; Faull, Richard L.M. ; Olson, James M. ; Jones, Lesley ; Luthi-Carter, Ruth

In: Human Molecular Genetics, 2006, vol. 15, no. 6, p. 965-977

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HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation

Träger, Ulrike ; Andre, Ralph ; Lahiri, Nayana ; Magnusson-Lind, Anna ; Weiss, Andreas ; Grueninger, Stephan ; McKinnon, Chris ; Sirinathsinghji, Eva ; Kahlon, Shira ; Pfister, Edith L. ; Moser, Roger ; Hummerich, Holger ; Antoniou, Michael ; Bates, Gillian P. ; Luthi-Carter, Ruth ; Lowdell, Mark W. ; Björkqvist, Maria ; Ostroff, Gary R. ; Aronin, Neil ; Tabrizi, Sarah J.

In: Brain, 2014, vol. 137, no. 3, p. 819-833

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A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease

Smith, Marianne R. ; Syed, Adeela ; Lukacsovich, Tamas ; Purcell, Judy ; Barbaro, Brett A. ; Worthge, Shane A. ; Wei, Stephen R. ; Pollio, Giuseppe ; Magnoni, Letizia ; Scali, Carla ; Massai, Luisa ; Franceschini, Davide ; Camarri, Michela ; Gianfriddo, Marco ; Diodato, Enrica ; Thomas, Russell ; Gokce, Ozgun ; Tabrizi, S.J. ; Caricasole, Andrea ; Landwehrmeyer, Bernard ; Menalled, Liliana ; Murphy, Carol ; Ramboz, Sylvie ; Luthi-Carter, Ruth ; Westerberg, Goran ; Marsh, J. Lawrence

In: Human Molecular Genetics, 2014, vol. 23, no. 11, p. 2995-3007

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Expression analysis of novel striatal-enriched genes in Huntington disease

Mazarei, Gelareh ; Neal, Scott J. ; Becanovic, Kristina ; Luthi-Carter, Ruth ; Simpson, Elizabeth M. ; Leavitt, Blair R.

In: Human Molecular Genetics, 2010, vol. 19, no. 4, p. 609-622

Consortium of Swiss Academic Libraries

In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons

Thomas, Elizabeth A. ; Coppola, Giovanni ; Tang, Bin ; Kuhn, Alexandre ; Kim, SoongHo ; Geschwind, Daniel H. ; Brown, Timothy B. ; Luthi-Carter, Ruth ; Ehrlich, Michelle E.

In: Human Molecular Genetics, 2011, vol. 20, no. 6, p. 1049-1060

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Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis

Becanovic, Kristina ; Pouladi, Mahmoud A. ; Lim, Raymond S. ; Kuhn, Alexandre ; Pavlidis, Paul ; Luthi-Carter, Ruth ; Hayden, Michael R. ; Leavitt, Blair R.

In: Human Molecular Genetics, 2010, vol. 19, no. 8, p. 1438-1452

Consortium of Swiss Academic Libraries

Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease

Thu, Doris C. V. ; Oorschot, Dorothy E. ; Tippett, Lynette J. ; Nana, Alissa L. ; Hogg, Virginia M. ; Synek, Beth J. ; Luthi-Carter, Ruth ; Waldvogel, Henry J. ; Faull, Richard L. M.

In: Brain, 2010, vol. 133, no. 4, p. 1094-1110

Consortium of Swiss Academic Libraries

Modulation of nucleosome dynamics in Huntington's disease

Stack, Edward C. ; Del Signore, Steven J. ; Luthi-Carter, Ruth ; Soh, Byoung Y. ; Goldstein, Darlene R. ; Matson, Samantha ; Goodrich, Sarah ; Markey, Angela L. ; Cormier, Kerry ; Hagerty, Sean W. ; Smith, Karen ; Ryu, Hoon ; Ferrante, Robert J.

In: Human Molecular Genetics, 2007, vol. 16, no. 10, p. 1164-1175

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