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S.8.1 An immunochip-based interrogation of scleroderma susceptibility variants

Charlesworth, J. ; Stankovich, J. ; Lewis, P. ; Byron, J. ; Stevens, W. ; Sahhar, J. ; Proudman, S. ; Roddy, J. ; Nash, P. ; Tymms, K. ; Brown, M. ; Zochling, J. ; Leask, A. ; Parapuram, S. ; Shiwen, X. ; Denton, C. ; Abraham, D. ; Liu, S. ; Vettori, S. ; Brock, M. ; Iwamoto, N. ; Maurer, B. ; Jungel, A. ; Gay, R. E. ; Calcagni, M. ; Valentini, G. ; Distler, J. H. ; Gay, S. ; Distler, O. ; Assassi, S. ; Mayes, M. ; Liu, X. ; Harper, B. ; Gonzalez, E. ; Draeger, H. ; Zhou, X. ; Khanna, D. ; Furst, D. ; Tan, F.

In: Rheumatology, 2012, vol. 51, p. ii15-ii17

S.6.1 β-catenin is a central mediator in SSc

Beyer, C. ; Schramm, A. ; Distler, A. ; Dees, C. ; Taketo, M. M. ; de Crombrugghe, B. ; Distler, O. ; Schett, G. ; Distler, J. H. W. ; Dees, C. ; Tomcik, M. ; Palumbo, K. ; Akhmetshina, A. ; Horn, A. ; Zerr, P. ; Distler, O. ; Schett, G. ; Distler, J. H. W. ; Distler, A. ; Palumbo, K. ; Dees, C. ; Bergmann, C. ; Venalis, P. ; Zerr, P. ; Horn, A. ; Beyer, C. ; MacDougald, O. A. ; Distler, O. ; Schett, G. ; Distler, J. H. W. ; Lagares, D. ; Busnadiego, O. ; Garcia-Fernandez, R. ; Kapoor, M. ; Liu, S. ; Carter, D. ; Abraham, D. ; Shi-Wen, X. ; Carreira, P. ; Fontaine, B. ; Shea, B. ; Tager, A. ; Leask, A. ; Lamas, S. ; Rodriguez-Pascual, F.

In: Rheumatology, 2012, vol. 51, p. ii12-ii14

Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry

Marathe, Swananda ; Liu, S. ; Brai, Emanuele ; Kaczarowski, M. ; Albéri, Lavinia

In: Cell Death & Differentiation, 2015, p. -

Neurological disorders such as Alzheimer’s disease, stroke and epilepsy are currently marred by the lack of effective treatments to prevent neuronal death. Erroneous cell cycle reentry (CCR) is hypothesized to have a causative role in neurodegeneration. We show that forcing S-phase reentry in cultured hippocampal neurons is sufficient to induce neurodegeneration. We found that kainic-acid...