Université de Fribourg

DNA origami as emerging technology for the engineering of fluorescent and plasmonic-based biosensors

Loretan, Morgane ; Domljanovic, Ivana ; Lakatos, Mathias ; Rüegg, Curzio ; Acuna, Guillermo P.

In: Materials, 2020, vol. 13, no. 9, p. 2185

DNA nanotechnology is a powerful and promising tool for the development of nanoscale devices for numerous and diverse applications. One of the greatest potential fields of application for DNA nanotechnology is in biomedicine, in particular biosensing. Thanks to the control over their size, shape, and fabrication, DNA origami represents a unique opportunity to assemble dynamic and complex...

Université de Fribourg

S-layer protein-AuNP systems for the colorimetric detection of metal and metalloid ions in water

Jung, J. ; Lakatos, Mathias ; Bengs, S. ; Matys, S. ; Raff, J. ; Blüher, A. ; Cuniberti, G.

In: Colloids and Surfaces B: Biointerfaces, 2019, vol. 183, p. 110284

Bacterial surface layer proteins (S-layer) possess unique binding properties for metal ions. By combining the binding capability of S-layer proteins with the optical properties of gold nanoparticles (AuNP), namely plasmonic resonance, a colorimetric detection system for metal and metalloid ions in water was developed. Eight S-layer proteins from different bacteria species were used for the...