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The eukaryote-specific N-terminal extension of ribosomal protein S31 contributes to the assembly and function of 40S ribosomal subunits

Fernández-Pevida, Antonio ; Martín-Villanueva, Sara ; Murat, Guillaume ; Lacombe, Thierry ; Kressler, Dieter ; Cruz, Jesús de la

In: Nucleic Acids Research, 2016, vol. 44, no. 16, p. 7777–7791

The archaea-/eukaryote-specific 40S-ribosomal-subunit protein S31 is expressed as an ubiquitin fusion protein in eukaryotes and consists of a conserved body and a eukaryote-specific N-terminal extension. In yeast, S31 is a practically essential protein, which is required for cytoplasmic 20S pre-rRNA maturation. Here, we have studied the role of the N-terminal extension of the yeast S31...