Università della Svizzera italiana

Dietary chloride deficiency syndrome : pathophysiology, history, and systematic literature review

Signorelli, Giulia C. ; Bianchetti, Mario G. ; Jermini, Luca M. M. ; Agostoni, Carlo ; Milani, Gregorio P. ; Simonetti, Giacomo D. ; Lava, Sebastiano A. G.

In: Nutrients, 2020, vol. 12, no. 11, p. 10 p

Metabolic alkalosis may develop as a consequence of urinary chloride (and sodium) wasting, excessive loss of salt in the sweat, or intestinal chloride wasting, among other causes. There is also a likely underrecognized association between poor salt intake and the mentioned electrolyte and acid–base abnormality. In patients with excessive loss of salt in the sweat or poor salt intake, the...