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Secreted venom allergen-like proteins of helminths: Conserved modulators of host responses in animals and plants

Wilbers, Ruud H. P. ; Schneiter, Roger ; Holterman, Martijn H. M. ; Drurey, Claire ; Smant, Geert ; Asojo, Oluwatoyin A. ; Maizels, Rick M. ; Lozano-Torres, Jose L.

In: PLOS Pathogens, 2018, vol. 14, no. 10, p. e1007300

Despite causing considerable damage to host tissue at the onset of parasitism, invasive helminths establish remarkably persistent infections in both animals and plants. Secretions released by these obligate parasites during host invasion are thought to be crucial for their persistence in infection. Helminth secretions are complex mixtures of molecules, most of which have unknown molecular...