Université de Fribourg

Metabolic programming of adipose tissue structure and function in male rat offspring by prenatal undernutrition

Thompson, Nichola ; Huber, Korinna ; Bedürftig, Mirijam ; Hansen, Kathrin ; Miles-Chan, Jennifer L. ; Breier, Bernhard H.

In: Nutrition & Metabolism, 2014, vol. 11, no. 1, p. 50

A number of different pathways to obesity with different metabolic outcomes are recognised. Prenatal undernutrition in rats leads to increased fat deposition in adulthood. However, the form of obesity is metabolically distinct from obesity induced through other pathways (e.g. diet-induced obesity). Previous rat studies have shown that maternal undernutrition during pregnancy led to insulin...