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Correlation of Growth and Breakdown of Major and Accessory Minerals in Metapelites from Campolungo, Central Alps

Gieré, Reto ; Rumble, Douglas ; Günther, Detlef ; Connolly, James ; Caddick, Mark J.

In: Journal of Petrology, 2011, vol. 52, no. 12, p. 2293-2334

cytotoxicity and genotoxicity of size-fractionated iron oxide (magnetite) in a549 human lung epithelial cells: role of ROS, JNK, and NF-κB

Könczöl, Mathias ; Ebeling, Sandra ; Goldenberg, Ella ; Treude, Fabian ; Gminski, Richard ; Gieré, Reto ; Grobéty, Bernard ; Rothen-Rutishauser, Barbara ; Merfort, Irmgard ; Mersch-Sundermann, Volker

In: Chemical Research in Toxycology, 2011, vol. 24, no. 9, p. 1460–1475

Airborne particulate matter (PM) of varying size and composition is known to cause health problems in humans. The iron oxide Fe₃O₄ (magnetite) may be a major anthropogenic component in ambient PM and is derived mainly from industrial sources. In the present study, we have investigated the effects of four different size fractions of magnetite on signaling pathways, free radical generation,...

Genotoxic effects of three selected black toner powders and their dimethyl sulfoxide extracts in cultured human epithelial A549 lung cells in vitro

Gminski, Richard ; Decker, Katharina ; Heinz, Christina ; Seidel, Albrecht ; Könczöl, Mathias ; Goldenberg, Ella ; Grobéty, Bernard ; Ebner, Winfried ; Gieré, Reto ; Mersch-Sundermann, Volker

In: Environmental and Molecular Mutagenesis, 2011, vol. 52, p. 296–309

Until now, the adverse effects of toner powders on humans have been considered to be minimal. However, several recent reports have suggested possible significant adverse health effects from toner dust inhalation. The aim of this study was to evaluate the genotoxic potential of black toner powders in vitro. For the study of DNA damage, A549 cells were exposed to toner-powder suspensions and to...

Airborne particles in the urban environment

Grobéty, Bernard ; Gieré, Reto ; Dietze, Volker ; Stille, Peter

In: Elements, 2010, vol. 6, no. 4, p. 229-234

Particulate matter is an important constituent of our atmosphere and has a critical impact on natural processes and human health. Although they are a minor component of the average global mass flux, anthropogenic particles are abundant in the urban environment, where they contribute substantially to air pollution. Particulate matter is routinely monitored in urban areas, but different particle...