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Nuclear import of dimerized ribosomal protein Rps3 in complex with its chaperone Yar1

Mitterer, Valentin ; Gantenbein, Nadine ; Birner-Gruenberger, Ruth ; Murat, Guillaume ; Bergler, Helmut ; Kressler, Dieter ; Pertschy, Brigitte

In: Scientific Reports, 2016, vol. 6, p. 36714

After their cytoplasmic synthesis, ribosomal proteins need to be transported into the nucleus, where they assemble with ribosomal RNA into pre-ribosomal particles. Due to their physicochemical properties, they need protection from aggregation on this path. Newly synthesized ribosomal protein Rps3 forms a dimer that is associated with one molecule of its specific chaperone Yar1. Here we report...